N-(Hydroxymethyl)phthalimide - CAS 118-29-6

Name: N-(Hydroxymethyl)phthalimide
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB004075
Product Name:	N-(Hydroxymethyl)phthalimide
CAS:	118-29-6
Synonyms:	2-(hydroxymethyl)isoindole-1,3-dione

Technical Data

IUPAC Name:	2-(hydroxymethyl)isoindole-1,3-dione
Description:	N-(Hydroxymethyl)phthalimide (CAS# 118-29-6) is used as a reactant in the synthesis of 5-[(3-aralkyl amido/imidoalkyl)phenyl]-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines as antiviral agents.
Molecular Weight:	177.16
Molecular Formula:	C9H7NO3
Canonical SMILES:	C1=CC=C2C(=C1)C(=O)N(C2=O)CO
InChI:	InChI=1S/C9H7NO3/c11-5-10-8(12)6-3-1-2-4-7(6)9(10)13/h1-4,11H,5H2
InChI Key:	MNSGOOCAMMSKGI-UHFFFAOYSA-N
Boiling Point:	332 °C at 760 mmHg
Melting Point:	140-145 °C
Purity:	95 %
Density:	1.462 g/cm³
Appearance:	White powder
Storage:	Store in a cool, dry place. Store in a tightly closed container.
MDL:	MFCD00005899
LogP:	0.17030

GHS Hazard Statement:	H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
Precautionary Statement:	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word:	Warning

Publication Number	Title	Priority Date
CN-113501777-A	Synthetic method of indoline-5-ylmethylamine dihydrochloride	20210716
CN-113292478-A	Synthesis method of N-hydroxymethyl phthalimide	20210616
CN-112661913-A	Preparation method of functional polycarboxylic acid water reducer capable of resisting flocculating agent in machine-made sand	20201223
CN-111518013-A	Phthalimide compound and preparation method thereof	20200526
CN-113493438-A	Tetrahydroisoquinoline compounds	20200320

PMID	Publication Date	Title	Journal
19073064	20070930	Determination of phosmet and its metabolites in olives by matrix solid-phase dispersion and gas chromatography-mass spectrometry	Talanta
17407773	20070702	Synthesis and anti-inflammatory activity of N-phthalimidomethyl 2,3-dideoxy- and 2,3-unsaturated glycosides	Carbohydrate research
13129307	20030924	Photolysis experiments on phosmet, an organophosphorus insecticide	Journal of agricultural and food chemistry
11376613	20010604	Synthesis and hypolipidemic activity of N-phthalimidomethyl tetra-O-acyl-alpha-D-mannopyranosides	Carbohydrate research

Complexity:	227
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	177.042593085
Formal Charge:	0
Heavy Atom Count:	13
Hydrogen Bond Acceptor Count:	3
Hydrogen Bond Donor Count:	1
Isotope Atom Count:	0
Monoisotopic Mass:	177.042593085
Rotatable Bond Count:	1
Topological Polar Surface Area:	57.6 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	1.5