IUPAC Name: | (2,5-dioxopyrrolidin-1-yl) 2-hydroxyacetate |
Description: | N-(Glycoloyloxy)-succinimide is used in the synthesis of Cletoquine (C573505). Cletoquine is a metabolite of Hydroxychloroquine (H916900), an anti-malarial; anti-rheumatic; lupus erythematosus suppressant. |
Molecular Weight: | 173.12 |
Molecular Formula: | C6H7NO5 |
Canonical SMILES: | C1CC(=O)N(C1=O)OC(=O)CO |
InChI: | InChI=1S/C6H7NO5/c8-3-6(11)12-7-4(9)1-2-5(7)10/h8H,1-3H2 |
InChI Key: | JLZNGFXJKPJSJO-UHFFFAOYSA-N |
Melting Point: | 103 - 108°C |
Solubility: | DMSO (Slightly), Methanol (Slightly) |
Appearance: | White to Off-White Solid |
Storage: | 4°C, Hygroscopic |
References: | Yarden, Y., et al. Nature, 323, 226 (1986); Seifert, R., et al. J. Biol. Chem., 264, 8771 (1989); Gahl, W., et al. Mol. Genet. Metab., 76, 234 (2002); Card, J., et al. Toxicol. Sci., 75, 169 (2003). |
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