N-Boc-trans-4-hydroxy-L-prolinol - CAS 61478-26-0
Catalog: |
BB031135 |
Product Name: |
N-Boc-trans-4-hydroxy-L-prolinol |
CAS: |
61478-26-0 |
Synonyms: |
Boc-Hyp-ol; Boc-Pro(4-Hydroxy)-ol; N-(t-Butoxycarbonyl)-trans-4-hydroxy-L-prolinol; (2S,4R)-1-(t-Butoxycarbonyl)-4-hydroxy-2-hydroxymethylpyrrolidine; (2S,4R)-Tert-butyl 4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate; Tert-butyl (2S,4R)-4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate |
IUPAC Name: | tert-butyl (2S,4R)-4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate |
Description: | A useful reactant used in the preparation of 4-purinylpyrrolidine nucleosides, kinase inhibitors and antibacterial agents. |
Molecular Weight: | 217.27 |
Molecular Formula: | C10H19NO4 |
Canonical SMILES: | CC(C)(C)OC(=O)N1CC(CC1CO)O |
InChI: | InChI=1S/C10H19NO4/c1-10(2,3)15-9(14)11-5-8(13)4-7(11)6-12/h7-8,12-13H,4-6H2,1-3H3/t7-,8+/m0/s1 |
InChI Key: | UFJNFQNQLMGUTQ-JGVFFNPUSA-N |
Boiling Point: | 340.3 °C / 760 mmHg |
Melting Point: | 85-87 °C |
Purity: | 98 % |
Density: | 1.19 g/cm3 |
Appearance: | White solid |
Storage: | Store at 2-8 °C |
MDL: | MFCD02094386 |
LogP: | 0.28690 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
WO-2021207172-A1 | Compounds and methods for targeted degradation of kras | 20200406 |
US-2019315732-A1 | Modulators of proteolysis and associated methods of use | 20180404 |
WO-2019195609-A2 | Modulators of proteolysis and associated methods of use | 20180404 |
AU-2019249231-A1 | Modulators of proteolysis and associated methods of use | 20180404 |
BR-112020020307-A2 | PROTEOLYSIS MODULATORS AND ASSOCIATED METHODS OF USE | 20180404 |
Complexity: | 236 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 2 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 217.13140809 |
Formal Charge: | 0 |
Heavy Atom Count: | 15 |
Hydrogen Bond Acceptor Count: | 4 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 217.13140809 |
Rotatable Bond Count: | 3 |
Topological Polar Surface Area: | 70 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0 |
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Alcohols and Derivatives
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS