N-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyladenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite - CAS 110782-31-5

Catalog: BB002673
Product Name: N-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyladenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
CAS: 110782-31-5
Synonyms: N6-Benzoyl-5'-O-DMT-2'-O-methyladenosine 3'-CE phosphoramidite; Dmt-2'-O-me-ra(bz) amidite; 2'-O-Methyl-rA(N-Bz)phosphoramidite; DMT-2'O-Methyl-rA(bz) Phosphoramidite; 5'-O-DMT-2'-O-Me-A(bz) phosphoramidite; 2'-OMe-Bz-A-CE-Phosphoramidite; N6-Benzoyl-5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-Adenosine-3'-CE-Phosphoramidite
N-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyladenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

Ordering Information

Catalog Size Price Stock Quantity
BB002673 5 g $199 In stock
Add to cart Inquiry

Technical Data

Patents

Computed Properties
IUPAC Name:N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-methoxyoxolan-2-yl]purin-6-yl]benzamide
Description:N-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyladenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is a modified phosphoramidite used in oligonucleotide synthesis. It features a benzoyl group protecting the adenine base, a 5'-dimethoxytrityl (DMT) group for 5'-hydroxyl protection, a 2'-O-methyl group to enhance stability, and a cyanoethyl (CE) group on the 3'-phosphoramidite for protection during synthesis. These modifications facilitate the incorporation of modified adenosine into oligonucleotides, improving their stability and performance in various applications such as genetic research and therapeutic development.
Molecular Weight:887.96
Molecular Formula:C48H54N7O8P
Canonical SMILES:CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OC)N2C=NC3=C2N=CN=C3NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC
InChI:InChI=1S/C48H54N7O8P/c1-32(2)55(33(3)4)64(61-28-14-27-49)63-42-40(62-47(43(42)59-7)54-31-52-41-44(50-30-51-45(41)54)53-46(56)34-15-10-8-11-16-34)29-60-48(35-17-12-9-13-18-35,36-19-23-38(57-5)24-20-36)37-21-25-39(58-6)26-22-37/h8-13,15-26,30-33,40,42-43,47H,14,28-29H2,1-7H3,(H,50,51,53,56)/t40-,42-,43-,47-,64?/m1/s1
InChI Key:AZCGOTUYEPXHMJ-PSVHYZMASA-N
Melting Point:93-95 °C
Purity:≥98% by HPLC
Solubility:Soluble in Acetonitrile (Sparingly), DMSO (Slightly), Methanol (Slightly)
Appearance:White to Off-white Solid
Storage:Store at -20 °C, under inert atmosphere
LogP:8.75108

Related Products

Online Inquiry
Verification code

Customer Support

If the product you need is not in our catalog, please contact us in time to submit your needs. You can help our website get better and better. Why not submit the request today?

Submit Requirement

Customer Centered

Global Delivery

Global Delivery

Warehouses in multiple cities to ensure fast delivery
Quality Assurance

Quality Assurance

Strict process parameter control to ensure product quality
Large Stock

Large Stock

> 20,000 building blocks and intermediates from stock
Process Scale-up

Process Scale-up

Process scale-up from lab to industrial scale
Flexible Batch Size

Flexible Batch Size

Flexible batch size for diverse industrial demands

Related Functional Groups

Carbonyl Compounds

Customers Also Viewed

INDUSTRY LEADERS TRUST OUR PRODUCTS

Phone

US & Canada (Toll free):

UK:

International:

E-mail & Fax

E-mail:

Fax:

 

Address

USA:

UK:

BOC Sciences

Copyright © 2024 BOC Sciences. All rights reserved.

Our Products

Amines and Anilines

Carbonyl Compounds

Nitrogen Compounds

Sulfur Compounds

Other Building Blocks

Fluorinated Building Blocks

Alcohols and Derivatives

Boronic Acids and Esters

Phosphorus Compounds

Oxygen Compounds

Heterocyclic Building Blocks

Allenes

Halides

Alkanes

Alkenes

Alkynes

Arenes

Inquiry Basket
Loading ......
Delete selectedGo to checkout