N-(4-Methoxy-2-methyl-6-quinolinyl)acetamide - CAS 100795-23-1

Catalog: BB060439
Product Name: N-(4-Methoxy-2-methyl-6-quinolinyl)acetamide
CAS: 100795-23-1
Synonyms: 6-Acetamido-4-methoxy-quinaldine
N-(4-Methoxy-2-methyl-6-quinolinyl)acetamide
IUPAC Name:N-(4-methoxy-2-methylquinolin-6-yl)acetamide
Description:N-(4-Methoxy-2-methyl-6-quinolinyl)acetamide is an intermediate in the synthesis of NSC 23766 (N900280), which is a highly soluble and membrane permeable Rac GTPase inhibitor. NSC 23766 inhibits Rac GTPase by targeting Rac activation by guanine nucleotide exchange factor (GEF). NSC 23766 has been shown to inhibit the anchorage-independent growth and invasion phenotypes of human prostate cancer PC-3 cells.
Molecular Weight:230.26
Molecular Formula:C13H14N2O2
Canonical SMILES:CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C)OC
InChI:InChI=1S/C13H14N2O2/c1-8-6-13(17-3)11-7-10(15-9(2)16)4-5-12(11)14-8/h4-7H,1-3H3,(H,15,16)
InChI Key:QEJJTUPQGGEUFD-UHFFFAOYSA-N
Solubility:Ethyl Acetate; Methanol
Appearance:Light Pink Solid
References:Gao, Y., et. al. Proc. Natl. Acad. Sci. U.S.A., 101, 7618, (2004); Akbar, H., et. al. Methods Enzymol, 406, 554 (2006).

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