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| Description: | N-[4-Cyano-2-(trifluoromethyl)phenyl]-2-methyl-2-propenamide is an intermediate in the synthesis of N-[4-Cyano-2-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide (C778035), a useful intermediate in the preparation of bicalutamide, enzalutamide and enobosarm derivatives carrying pentafluorosulfanyl (SF5) and pentafluoroethyl (C2F5) substituents which are potential anti-tumor drugs, and a positional isomer of C987585; bicalutamide impurity. |
| Molecular Weight: | 254.21 |
| Molecular Formula: | C12H9F3N2O |
| References: | Pertusati, F., et al. Eur. J. Med. Chem., 180, 1 (2019); Bassetto, M., et al. Eur. J. Med. Chem., 118, 230 (2016). |
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