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N-[[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]phenyl]methylene]-4-fluorobenzenamine

N-[[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]phenyl]methylene]-4-fluorobenzenamine - CAS 179411-51-9

Catalog:	BB066843
Product Name:	N-[[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]phenyl]methylene]-4-fluorobenzenamine
CAS:	179411-51-9

Technical Data

Description:	N-[[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]phenyl]methylene]-4-fluorobenzenamine is an intermediate in the synthesis of (3S,4S,3'S)-Ezetimbe (E975040), which is a 3-epimer impurity of Ezetimibe (E975000), a cholesterol absorption inhibitor.
Molecular Weight:	329.48
Molecular Formula:	C19H24FNOSi
Solubility:	DCM
Appearance:	Off-White Solid
References:	van Heek, M., at al. J. Pharmacol. Exp. Ther., 283, 157 (1997), van Heek, M., at al. Brit. J. Pharmacol., 129, 1748 (2000).

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