Description: | N-(3,4-Dichlorophenyl)-7-fluoro-6-nitroquinazolin-4-amine is a useful synthetic intermediate in the synthesis of Afatinib (A355300); an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder. |
Molecular Weight: | 353.14 |
Molecular Formula: | C14H7Cl2FN4O2 |
References: | Schroeder, J., et al. PCT Int. Appl. WO 2007085638 A1 20070802. Aug 2, 2007. |
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