N-(2-Hydroxypropyl)-2-methyl-prop-2-enamide - CAS 21442-01-3

Name: N-(2-Hydroxypropyl)-2-methyl-prop-2-enamide
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB016866
Product Name:	N-(2-Hydroxypropyl)-2-methyl-prop-2-enamide
CAS:	21442-01-3
Synonyms:	N-(2-hydroxypropyl)-2-methylprop-2-enamide

Technical Data

IUPAC Name:	N-(2-hydroxypropyl)-2-methylprop-2-enamide
Description:	N-(2-hydroxypropyl)methacrylamide (HPMA) is a difunctional, hydrolytically stable, hydrophilic monomer, a building blocks of modified and new biomaterials.
Molecular Weight:	143.18
Molecular Formula:	C7H13NO2
Canonical SMILES:	CC(CNC(=O)C(=C)C)O
InChI:	InChI=1S/C7H13NO2/c1-5(2)7(10)8-4-6(3)9/h6,9H,1,4H2,2-3H3,(H,8,10)
InChI Key:	OKPYIWASQZGASP-UHFFFAOYSA-N
Boiling Point:	321.2±34.0 °C (Predicted)
Melting Point:	67.92 °C
Purity:	98 %
Density:	1.002 g/cm³
Appearance:	Powder
Storage:	Store at 4 degrees celsius
LogP:	0.45040

GHS Hazard Statement:	H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
Precautionary Statement:	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word:	Warning

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PMID	Publication Date	Title	Journal
23034926	20121015	Poly(2-oxazoline)s--are they more advantageous for biomedical applications than other polymers?	Macromolecular rapid communications
22795544	20121001	Anti-CD20 multivalent HPMA copolymer-Fab' conjugates for the direct induction of apoptosis	Biomaterials
22930486	20121001	Surfaces resistant to fouling from biological fluids: towards bioactive surfaces for real applications	Macromolecular bioscience
22746534	20120813	Reduction-responsive disassemblable core-cross-linked micelles based on poly(ethylene glycol)-b-poly(N-2-hydroxypropyl methacrylamide)-lipoic acid conjugates for triggered intracellular anticancer drug release	Biomacromolecules
22793269	20120813	Macromolecular HPMA-based nanoparticles with cholesterol for solid-tumor targeting: detailed study of the inner structure of a highly efficient drug delivery system	Biomacromolecules

Complexity:	143
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	143.094628657
Formal Charge:	0
Heavy Atom Count:	10
Hydrogen Bond Acceptor Count:	2
Hydrogen Bond Donor Count:	2
Isotope Atom Count:	0
Monoisotopic Mass:	143.094628657
Rotatable Bond Count:	3
Topological Polar Surface Area:	49.3 Å²
Undefined Atom Stereocenter Count:	1
Undefined Bond Stereocenter Count:	0
XLogP3:	0.3