N-(2-Hydroxyethyl)maleimide - CAS 1585-90-6
Catalog: |
BB011436 |
Product Name: |
N-(2-Hydroxyethyl)maleimide |
CAS: |
1585-90-6 |
Synonyms: |
Mal-PEG1-OH; Maleimide-PEG1-alcohol; 1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione; 1-(2-hydroxyethyl)-2,5-dihydro-1H-pyrrole-2,5-dione; 1H-Pyrrole-2,5-dione, 1-(2-hydroxyethyl)-; 2-Maleimidylethanol |
Related CAS: | 58914-60-6 (polymer) 894072-45-8 (polymer) 2569686-51-5 (polymer)
|
IUPAC Name: | 1-(2-hydroxyethyl)pyrrole-2,5-dione |
Description: | N-(2-Hydroxyethyl)maleimide is a PEG linker containing a maleimide group and a hydroxyl group. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of a biomolecule with a thiol. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The hydrophilic PEG spacer increases solubility in aqueous media. |
Molecular Weight: | 141.12 |
Molecular Formula: | C6H7NO3 |
Canonical SMILES: | C1=CC(=O)N(C1=O)CCO |
InChI: | InChI=1S/C6H7NO3/c8-4-3-7-5(9)1-2-6(7)10/h1-2,8H,3-4H2 |
InChI Key: | AXTADRUCVAUCRS-UHFFFAOYSA-N |
Boiling Point: | 130°C at 0.005 mmHg |
Melting Point: | 66-67°C |
Purity: | ≥95% |
Density: | 1.395 g/cm3 |
Appearance: | Pale Yellow or Colorless Oily Matter |
Storage: | Store at 2-8°C |
LogP: | -1.15840 |
GHS Hazard Statement: | H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] |
Precautionary Statement: | P264, P280, P305+P351+P338, and P337+P313 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-113150345-A | High-strength moisture-proof polyurethane molded plate and preparation method thereof | 20210528 |
CN-112795300-A | UV coating and preparation method thereof | 20201230 |
CN-112358596-A | Cardanol-based shape memory polymer and preparation method thereof | 20201029 |
CN-112225876-A | Preparation method of rosin-based self-repairing polyurethane based on Diels-Alder reaction | 20201020 |
CN-111920959-A | ROS (reactive oxygen species) -responsive heparin polysaccharide nano prodrug compound based on click reaction, nano preparation, and preparation method and application thereof | 20200724 |
PMID | Publication Date | Title | Journal |
21371790 | 20110501 | Bivalent bendamustine and melphalan derivatives as anticancer agents | European journal of medicinal chemistry |
20849062 | 20101020 | Optimization of the N-lost drugs melphalan and bendamustine: synthesis and cytotoxicity of a new set of dendrimer-drug conjugates as tumor therapeutic agents | Bioconjugate chemistry |
Complexity: | 179 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 141.042593085 |
Formal Charge: | 0 |
Heavy Atom Count: | 10 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 141.042593085 |
Rotatable Bond Count: | 2 |
Topological Polar Surface Area: | 57.6 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -0.1 |
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Carbonyl Compounds
-
[89908-23-6]C23H22N2O5
2-Propenoic acid, 2-(3',3'-dimethyl-6-nitrospiro[2H-1-benzopyran-2,2'-[2H]indol]-1'(3'H)-yl)ethyl ester
-
[87-88-7]C6H2Cl2O4
Chloranilic acid
-
[1431966-64-1]C10H17ClN2O2S
1-{2-[(3-Methoxypropyl)amino]-4-methyl-1,3-thiazol-5-yl}ethanone hydrochloride
-
[253429-30-0]C12H16BrFO3
1-Bromo-2-(2,2-diethoxyethoxy)-4-fluorobenzene
-
[69616-74-6]C18H18O6
2',4-Dihydroxy-3',4',6'-trimethoxychalcone
-
[328270-02-6]C11H16N2OS
2-Amino-6-ethyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS