Murrayafoline A - CAS 4532-33-6
Catalog: |
BB025835 |
Product Name: |
Murrayafoline A |
CAS: |
4532-33-6 |
Synonyms: |
1-methoxy-3-methyl-9H-carbazole |
IUPAC Name: | 1-methoxy-3-methyl-9H-carbazole |
Description: | Murrayafoline A is a natural compound which can be isolated from Clausena heptaphylla, Murraya euchrestifolia, etc. |
Molecular Weight: | 211.26 |
Molecular Formula: | C14H13NO |
Canonical SMILES: | CC1=CC2=C(C(=C1)OC)NC3=CC=CC=C32 |
InChI: | InChI=1S/C14H13NO/c1-9-7-11-10-5-3-4-6-12(10)15-14(11)13(8-9)16-2/h3-8,15H,1-2H3 |
InChI Key: | HDETUOZJFUNSKG-UHFFFAOYSA-N |
Purity: | 98% |
Appearance: | Solid |
LogP: | 3.63810 |
Publication Number | Title | Priority Date |
WO-2021074614-A1 | Treatment or prevention of leukaemia | 20191014 |
CN-110330486-A | Carbazoles oxadiazoles conjugate and its preparation method and application | 20190730 |
CN-109627205-A | The preparation method and applications of a kind of carbazyl Isopropanolamine derivatives | 20190111 |
CN-109438330-A | Sulphonyl carbazole alcoholic compound and its preparation method and application | 20181229 |
CN-109485641-A | Uracil-carbazoles conjugate, synthesis and its application of a kind of amide key connection | 20180719 |
PMID | Publication Date | Title | Journal |
22875057 | 20120928 | Novel approach to biscarbazole alkaloids via Ullmann coupling--synthesis of murrastifoline-A and bismurrayafoline-A | Organic & biomolecular chemistry |
21879331 | 20120401 | Apoptosis of HL-60 leukemia cells induced by carbazole alkaloids isolated from Murraya euchrestifolia | Journal of natural medicines |
19962966 | 20100101 | Murrayafoline A attenuates the Wnt/beta-catenin pathway by promoting the degradation of intracellular beta-catenin proteins | Biochemical and biophysical research communications |
18543991 | 20080704 | Intramolecular Pd(II)-catalyzed oxidative biaryl synthesis under air: reaction development and scope | The Journal of organic chemistry |
18629709 | 20080101 | 1-O-Substituted derivatives of murrayafoline A and their antifungal properties | Natural product research |
Complexity: | 255 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 211.099714038 |
Formal Charge: | 0 |
Heavy Atom Count: | 16 |
Hydrogen Bond Acceptor Count: | 1 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 211.099714038 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 25 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 3.7 |
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