Moroxydine - CAS 3731-59-7
Catalog: |
BB023256 |
Product Name: |
Moroxydine |
CAS: |
3731-59-7 |
Synonyms: |
N-(diaminomethylidene)-4-morpholinecarboximidamide; N-(diaminomethylidene)morpholine-4-carboximidamide |
Application: |
Antiviral Agents |
IUPAC Name: | N-(diaminomethylidene)morpholine-4-carboximidamide |
Description: | Moroxydine is used as an antiviral drug against multiple DNA and RNA virus. |
Molecular Weight: | 171.20 |
Molecular Formula: | C6H13N5O |
Canonical SMILES: | C1COCCN1C(=N)N=C(N)N |
InChI: | InChI=1S/C6H13N5O/c7-5(8)10-6(9)11-1-3-12-4-2-11/h1-4H2,(H5,7,8,9,10) |
InChI Key: | KJHOZAZQWVKILO-UHFFFAOYSA-N |
Boiling Point: | 327 °C at 760 mmHg |
Melting Point: | 211-214 °C (lit.) |
Flash Point: | 151.6°C |
Purity: | 97 % |
Density: | 1.51 g/cm3 |
Solubility: | In vitro: H2O:≥44mg / mL(211.88 mM) |
Appearance: | Solid powder |
Storage: | Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month |
MDL: | MFCD00012798 |
LogP: | -0.03500 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
US-2020325182-A1 | Alphaherpesvirus glycoprotein d-encoding nucleic acid constructs and methods | 20200611 |
US-10980756-B1 | Methods of treatment | 20200316 |
WO-2021123121-A1 | Lipid-based compositions comprising lipophilic salts and acidic ph modifiers | 20191218 |
US-2021177858-A1 | Compositions and methods for controlling cerumen production | 20191213 |
WO-2021119276-A1 | Compositions and methods for controlling cerumen production | 20191213 |
PMID | Publication Date | Title | Journal |
22547055 | 20120601 | Exploration of biguanido-oxovanadium complexes as potent and selective inhibitors of protein tyrosine phosphatases | Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine |
22346740 | 20120201 | Using functional signatures to identify repositioned drugs for breast, myelogenous leukemia and prostate cancer | PLoS computational biology |
22629602 | 20110901 | [The influence of N-[imino(1-piperidinyl)methyl]guanidine and N-[imino(4-morpholinyl)methyl]guanidine on citrate content, aconitase and citrate synthase activities at ischemia-reperfusion of rats brain] | Biomeditsinskaia khimiia |
21657060 | 20110301 | [Separation of bases, phenols and pharmaceuticals on ionic liquid-modified silica stationary phase with pure water as mobile phase] | Se pu = Chinese journal of chromatography |
20396755 | 20091001 | Effect of N-[Imino(4-morpholyl)methyl]guanidine on the oxidative status in rats with toxic hepatitis | Bulletin of experimental biology and medicine |
Complexity: | 192 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 171.11201006 |
Formal Charge: | 0 |
Heavy Atom Count: | 12 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 3 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 171.11201006 |
Rotatable Bond Count: | 2 |
Topological Polar Surface Area: | 101 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -1.6 |
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