Methylbenzyl Nimesulide

Catalog:	BB076072
Product Name:	Methylbenzyl Nimesulide
Synonyms:	2-(4-(Benzyloxy)phenoxy)-1-((methylsulfonyl)methyl)-4-nitrobenzene

Technical Data

Description:	Methylbenzyl Nimesulide is an intermediate in the synthesis of 4'-Hydroxy Nimesulide (H948560), the main metabolite of Nimesulide (N477500), an antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-alpha production.
Molecular Weight:	414.43
Molecular Formula:	C20H18N2O6S
References:	Pairet, M., et al. Inflamm. Res., 47, S93 (1998); Fukutake, M., et al. Carcinogenesis, 19, 1939 (1998); Okajima., E., et al. Cancer Res., 58, 3028 (1998); Azab, A., et al. Life Sci., 63, 323 (1998).

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