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| Description: | Methyl (Z)-3-(Methoxy(phenyl)methylene)-2-oxoindoline-7-carboxylate is an intermediate in the synthesis of Desmethyl 7-Methoxycarbonyl Nintedanib (D293098), an impurity of Intedanib (I666650), which is an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases. it is an indolinone as triple angiokinase inhibitors and an antitumor agent. |
| Molecular Weight: | 309.32 |
| Molecular Formula: | C18H15NO4 |
| References: | Sun, L., et al. J. Med. Chem., 41, 2588 (1998); Xie, H., et al. J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al. Cancer Res., 68, 4774 (2008); Roth, G., et al. J. Med. Chem., 58, 1053 (2015). |
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