α-Methyl-α-phenylsuccinimide - CAS 1497-17-2

Catalog:	BB010440
Product Name:	α-Methyl-α-phenylsuccinimide
CAS:	1497-17-2
Synonyms:	3-methyl-3-phenylpyrrolidine-2,5-dione

Technical Data

Safety and Hazards

Patents

Literatures

Computed Properties

IUPAC Name:	3-methyl-3-phenylpyrrolidine-2,5-dione
Description:	A metabolite of calcium channel succinimide antiepileptic drug Methsuximide. Anticonvulsant.
Molecular Weight:	189.21
Molecular Formula:	C11H11NO2
Canonical SMILES:	CC1(CC(=O)NC1=O)C2=CC=CC=C2
InChI:	InChI=1S/C11H11NO2/c1-11(7-9(13)12-10(11)14)8-5-3-2-4-6-8/h2-6H,7H2,1H3,(H,12,13,14)
InChI Key:	UDESUGJZUFALAM-UHFFFAOYSA-N
Boiling Point:	371.1 °C at 760 mmHg
Melting Point:	83-85 °C (lit.)
Purity:	95 %
Density:	1.179 g/cm³
Appearance:	Off-white solid
MDL:	MFCD00005496
LogP:	1.31960

Publication Number	Title	Priority Date
CN-113307977-A	Dispersant polymers and compositions including the same	20200226
EP-3872140-A1	Dispersant polymer and composition comprising the same	20200226
US-2021261719-A1	Dispersant polymer and composition comprising the same	20200226
CN-112218913-A	Porous body and method for producing porous body	20190304
EP-3789444-A1	Porous body, and method for producing porous body	20190304

PMID	Publication Date	Title	Journal
15078185	20040401	Pharmacology of recombinant low-voltage activated calcium channels	Current drug targets. CNS and neurological disorders
11641441	20011101	Block of cloned human T-type calcium channels by succinimide antiepileptic drugs	Molecular pharmacology
11407955	20010301	Effective and safe but forgotten: methsuximide in intractable epilepsies in childhood	Seizure
2169941	19900801	Differential effects of petit mal anticonvulsants and convulsants on thalamic neurones: calcium current reduction	British journal of pharmacology
38736	19790601	Inhibitory effects of anticonvulsant drugs on cyclic nucleotide accumulation in brain	Annals of neurology

Related Products

Online Inquiry

Name:

* Phone:

* Service & Products of Interested:

Project Description:

* Quantity:

* Email:

* Verification Code:

Customer Support

If the product you need is not in our catalog, please contact us in time to submit your needs. You can help our website get better and better. Why not submit the request today?

Submit Requirement

Customer Centered

Global Delivery

Warehouses in multiple cities to ensure fast delivery

Quality Assurance

Strict process parameter control to ensure product quality

Large Stock

> 20,000 building blocks and intermediates from stock

Process Scale-up

Process scale-up from lab to industrial scale

Flexible Batch Size

Flexible batch size for diverse industrial demands

Related Functional Groups

Carbonyl Compounds

[89908-23-6]
2-Propenoic acid, 2-(3',3'-dimethyl-6-nitrospiro[2H-1-benzopyran-2,2'-[2H]indol]-1'(3'H)-yl)ethyl ester
[5650-34-0]
Oxiran-2-yl(phenyl)methanone
[17746-05-3]
Undecanoyl chloride
[959574-98-2]
(3-Phenyl-1H-pyrazol-1-yl)acetic acid
[35153-16-3]
(Z)-10-Tetradecenyl Acetate
[1018141-88-2]
1-(2-Cyanoethyl)-3-methyl-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

GHS Hazard Statement:	H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
Precautionary Statement:	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word:	Warning

Complexity:	269
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	189.078978594
Formal Charge:	0
Heavy Atom Count:	14
Hydrogen Bond Acceptor Count:	2
Hydrogen Bond Donor Count:	1
Isotope Atom Count:	0
Monoisotopic Mass:	189.078978594
Rotatable Bond Count:	1
Topological Polar Surface Area:	46.2 Å²
Undefined Atom Stereocenter Count:	1
Undefined Bond Stereocenter Count:	0
XLogP3:	1