Methyl dichlorophosphate - CAS 677-24-7
Catalog: |
BB033376 |
Product Name: |
Methyl dichlorophosphate |
CAS: |
677-24-7 |
Synonyms: |
dichlorophosphoryloxymethane |
IUPAC Name: | dichlorophosphoryloxymethane |
Description: | Methyl dichlorophosphate (CAS# 677-24-7) is useful for the synthesis of novel polycyclic phosphates. Also, it is used to synthesize potent C-10 carba artemisinin dimers against P. falciparum malaria parasites and HL-60 cancer cells. |
Molecular Weight: | 148.91 |
Molecular Formula: | CH3Cl2O2P |
Canonical SMILES: | COP(=O)(Cl)Cl |
InChI: | InChI=1S/CH3Cl2O2P/c1-5-6(2,3)4/h1H3 |
InChI Key: | SNVCRNWSNUUGEA-UHFFFAOYSA-N |
Boiling Point: | 62-64 °C15 mmHg (lit.) |
Purity: | > 95.0 % (T) |
Density: | 1.488 g/cm3 |
Appearance: | Colorless to light yellow clear liquid |
LogP: | 2.21850 |
GHS Hazard Statement: | H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] |
Precautionary Statement: | P260, P264, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P363, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
CN-113336794-A | Novel saccharide bio-based cyclic phosphorus/phosphonate and preparation method and application thereof | 20210531 |
CN-112851909-A | Storage-stable polyisocyanate composition | 20210114 |
CN-112680972-A | Flame-retardant polyester fabric and preparation method thereof | 20210111 |
CN-112480565-A | Phosphorus-containing cardanol-based flame-retardant plasticizer for modified polyvinyl chloride and preparation method and application thereof | 20201127 |
CN-112661788-A | Phosphorus-containing polyaspartic acid ester and preparation method and application thereof | 20201117 |
PMID | Publication Date | Title | Journal |
16557311 | 20060407 | Synthesis of oligosaccharides corresponding to Vibrio cholerae O139 polysaccharide structures containing dideoxy sugars and a cyclic phosphate | Organic & biomolecular chemistry |
15027860 | 20040325 | Enzymatic release of antitumor ether lipids by specific phospholipase A2 activation of liposome-forming prodrugs | Journal of medicinal chemistry |
Complexity: | 75.6 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 147.9247717 |
Formal Charge: | 0 |
Heavy Atom Count: | 6 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 147.9247717 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 26.3 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1 |
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