![Methyl 8-Oxo-1,4-dioxaspiro[4.5]decane-7-carboxylate](https://resource.bocsci.com/structure/52506-21-5.gif)
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| IUPAC Name: | methyl 8-oxo-1,4-dioxaspiro[4.5]decane-7-carboxylate |
| Description: | Methyl 8-Oxo-1,4-dioxaspiro[4.5]decane-7-carboxylate is a useful research intermediate. It is used in the practical synthesis of the key intermediates of substituted analogs of Huperzine A. Huperzine A is a potent reversible inhibitor of acetylcholinesterase (AChE) , an important psychotherapeutic agent for improving cognitive function in Alzheimer's patients. |
| Molecular Weight: | 214.21 |
| Molecular Formula: | C10H14O5 |
| Canonical SMILES: | COC(=O)C1CC2(CCC1=O)OCCO2 |
| InChI: | InChI=1S/C10H14O5/c1-13-9(12)7-6-10(3-2-8(7)11)14-4-5-15-10/h7H,2-6H2,1H3 |
| InChI Key: | HDBHPQJOSZBECI-UHFFFAOYSA-N |
| References: | Zhou, G., et al. Synth. Commun., 32, 37 (2002); Kozikowski, A. P., et al. J. Am. Chem. Soc., 118, 11357 (1996). |
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