Methyl 6-(Hydroxymethyl)pyridine-2-carboxylate - CAS 39977-44-1
Catalog: |
BB024236 |
Product Name: |
Methyl 6-(Hydroxymethyl)pyridine-2-carboxylate |
CAS: |
39977-44-1 |
Synonyms: |
6-(hydroxymethyl)-2-pyridinecarboxylic acid methyl ester; methyl 6-(hydroxymethyl)pyridine-2-carboxylate |
IUPAC Name: | methyl 6-(hydroxymethyl)pyridine-2-carboxylate |
Description: | Methyl 6-(Hydroxymethyl)pyridine-2-carboxylate (CAS# 39977-44-1) is a chemical compound used in the synthesis of Losartan (L470500) derivatives as AT1 antagonists in the preparation of antihypertensive agents. Also used to prepare telomerase inhibitors for in vivo inhibitory activity. |
Molecular Weight: | 167.16 |
Molecular Formula: | C8H9NO3 |
Canonical SMILES: | COC(=O)C1=NC(=CC=C1)CO |
InChI: | InChI=1S/C8H9NO3/c1-12-8(11)7-4-2-3-6(5-10)9-7/h2-4,10H,5H2,1H3 |
InChI Key: | DVIUNMLAPDJWHL-UHFFFAOYSA-N |
Boiling Point: | 327.3 °C at 760 mmHg |
Density: | 1.244 g/cm3 |
Appearance: | White or off-white solid |
MDL: | MFCD03840850 |
LogP: | 0.36050 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
WO-2021185256-A1 | Substituted pyrimidine or pyridine amine derivative, composition thereof, and medical use thereof | 20200316 |
CN-112707873-A | Substituted oxazole derivative and application thereof in medicine | 20191025 |
WO-2020247789-A1 | Processes for preparing aminopyrimidine compounds | 20190606 |
WO-2020198537-A1 | Modulators of mas-related g-protein receptor x4 and related products and methods | 20190328 |
US-2021032213-A1 | Modulators of mas-related g-protein receptor x4 and related products and methods | 20190328 |
Complexity: | 160 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 167.058243149 |
Formal Charge: | 0 |
Heavy Atom Count: | 12 |
Hydrogen Bond Acceptor Count: | 4 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 167.058243149 |
Rotatable Bond Count: | 3 |
Topological Polar Surface Area: | 59.4 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.2 |
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