methyl 5-methylpyrazine-2-carboxylate - CAS 41110-33-2
Catalog: |
BB024788 |
Product Name: |
methyl 5-methylpyrazine-2-carboxylate |
CAS: |
41110-33-2 |
Synonyms: |
5-methyl-2-pyrazinecarboxylic acid methyl ester; methyl 5-methylpyrazine-2-carboxylate |
IUPAC Name: | methyl 5-methylpyrazine-2-carboxylate |
Description: | methyl 5-methylpyrazine-2-carboxylate (CAS# 41110-33-2) is an intermediate in the synthesis of 4-[β-(5-Methylpyrazinyl-2-carboxamido)ethyl]benzene Sulfonamide which itself is an intermediate in the synthesis of Glipizide (G410225). |
Molecular Weight: | 152.15 |
Molecular Formula: | C7H8N2O2 |
Canonical SMILES: | CC1=NC=C(N=C1)C(=O)OC |
InChI: | InChI=1S/C7H8N2O2/c1-5-3-9-6(4-8-5)7(10)11-2/h3-4H,1-2H3 |
InChI Key: | CRBOSZMVDHYLJE-UHFFFAOYSA-N |
Boiling Point: | 234.1 °C at 760 mmHg |
Density: | 1.169 g/cm3 |
Appearance: | Brown powder |
MDL: | MFCD04116910 |
LogP: | 0.57160 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-111500614-A | Plasmid for efficiently catalyzing L-threonine to synthesize 2,5-DMP (dimethyl formamide) and construction and application thereof | 20200519 |
CN-110684705-A | Recombinant escherichia coli for producing 5-methylpyrazine-2 carboxylic acid | 20191031 |
CN-110527656-A | Efficiently synthesize engineering bacteria and its construction method and the application of 5-Methylpyrazine-2-carboxylic acid | 20190904 |
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PMID | Publication Date | Title | Journal |
8765523 | 19960816 | Quantitative structure-activity relationships for the in vitro antimycobacterial activity of pyrazinoic acid esters | Journal of medicinal chemistry |
7562923 | 19950929 | Pyrazinoic acid esters with broad spectrum in vitro antimycobacterial activity | Journal of medicinal chemistry |
Complexity: | 149 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 152.058577502 |
Formal Charge: | 0 |
Heavy Atom Count: | 11 |
Hydrogen Bond Acceptor Count: | 4 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 152.058577502 |
Rotatable Bond Count: | 2 |
Topological Polar Surface Area: | 52.1 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.2 |
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