Methyl 4-[(3-chloro-2-fluorophenyl)methyl]-1-piperazinecarboxylate - CAS 1309439-45-9

Catalog: BB060194
Product Name: Methyl 4-[(3-chloro-2-fluorophenyl)methyl]-1-piperazinecarboxylate
CAS: 1309439-45-9
Description:Methyl 4-[(3-chloro-2-fluorophenyl)methyl]-1-piperazinecarboxylate is an intermediate in the synthesis of CK 1827452 (C544000), a promising new drug in systolic heart failure. It accelerates the transition of myosin into the force-generating state without affecting cardiac myocyte calcium homeostasis. CK 1827452 increases cardiac function by increasing the duration of ejection without changing the rates of contraction.
Molecular Weight:286.73
Molecular Formula:C13H16ClFN2O2
References:Meijs, M. et al. Eur. J. Heart. Fail., 14, 232 (2012); Malik, F. et al. J. Mol. Cell. Card., 51, 454 (2011).

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