Description: | Methyl 3-Iodo-4-methyl-d3-benzoate-2,5,6-d3 is the labeled form of Methyl 3-Iodo-4-methylbenzoate (M313750) is used as a reagent in the synthesis of [(pyrazolo[1,5-a]pyridmidinyl)ethynyl]benzamides as selective discoidin domain receptor 1 (DDR1) inhibitors. Also used as a reagent in the preparation of orally bioavailable GZD824 targeting Breakpoint Cluster Region-Abelson (Bcr-Abl) kinase and overcoming antitumor drug resistance. |
Molecular Weight: | 282.11 |
Molecular Formula: | C9H3D6IO2 |
References: | Gao, M., et al. J. Med. Chem., 56, 3281 (2013); Ren, X., et al. J. Med. Chem., 56, 879 (2013). |
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