Memantine USP Related Compound B - CAS 707-37-9
Catalog: |
BB034229 |
Product Name: |
Memantine USP Related Compound B |
CAS: |
707-37-9 |
Synonyms: |
USP Memantine Related Compound B; Memantine Related Compound B; 3,5-Dimethyladamantane-1-ol; 3,5-Dimethyl-1-adamantanol; Tricyclo[3.3.1.13,7]decan-1-ol, 3,5-dimethyl-; 1-Adamantanol, 3,5-dimethyl-; 3,5-Dimethyltricyclo[3.3.1.13,7]decan-1-ol; 1,3-Dimethyl-5-adamantanol; 1,3-Dimethyl-5-hydroxyadamantane; 1-Hydroxy-3,5-dimethyladamantane; 3,5-Dimethyl-1-hydroxyadamantane; 5,7-Dimethyl-3-adamantanol; NSC 102294 |
IUPAC Name: | 3,5-dimethyladamantan-1-ol |
Description: | Memantine USP Related Compound B is an impurity of Memantine, which is an N-methyl D-aspartate (NMDA) antagonist used to slow the progression of moderate-to-severe Alzheimer's disease. |
Molecular Weight: | 180.29 |
Molecular Formula: | C12H20O |
Canonical SMILES: | CC12CC3CC(C1)(CC(C3)(C2)O)C |
InChI: | InChI=1S/C12H20O/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9,13H,3-8H2,1-2H3 |
InChI Key: | LBWCITVBZLTEKW-UHFFFAOYSA-N |
Boiling Point: | 247.2±8.0°C at 760 mmHg |
Melting Point: | 92-98°C |
Flash Point: | 101.8°C |
Purity: | ≥95% |
Density: | 1.121±0.06 g/cm3 |
Solubility: | Soluble in Chloroform (Slightly), Methanol (Slightly) |
Appearance: | White to Off-white Solid |
Storage: | Store at 2-8°C |
MDL: | MFCD00074775 |
LogP: | 2.72770 |
Refractive Index: | 1.572 |
GHS Hazard Statement: | H315 (75%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-111233670-A | Memantine hydrochloride impurity compound and preparation method thereof | 20200309 |
WO-2021162746-A1 | Propylene polymers obtained using transition metal bis(phenolate) catalyst complexes and homogeneous process for production thereof | 20200211 |
JP-2021116343-A | Resin composition for forming a phase-separated structure, a method for producing a structure containing a phase-separated structure, and a block copolymer. | 20200124 |
KR-20210095804-A | Resin composition for forming phase-separated structure, method for producing structure including phase-separated structure, and block copolymer | 20200124 |
US-2021230340-A1 | Resin composition for forming phase-separated structure, method for producing structure including phase-separated structure, and block copolymer | 20200124 |
Complexity: | 240 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 180.151415257 |
Formal Charge: | 0 |
Heavy Atom Count: | 13 |
Hydrogen Bond Acceptor Count: | 1 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 180.151415257 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 20.2 Å2 |
Undefined Atom Stereocenter Count: | 2 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 3.5 |
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