Imatinib RC11

Catalog:	BB060802
Product Name:	Imatinib RC11
Synonyms:	1,3-Bis(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)urea

Technical Data

Description:	Imatinib RC11 is an impurity of Imatinib (Gleevec) (G407000), which is a tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). It is a COVID19-related research product.
Molecular Weight:	580.66
Molecular Formula:	C33H28N10O
Melting Point:	>230°C (dec.)
Solubility:	DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
Appearance:	White to Off-White Solid
Storage:	-20°C Freezer
References:	Schindler, T., et al. Science, 289, 1938 (2000), Drucker, B.J., et al. N. Engl. J. Med., 344, 1031 (2001),.

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