Description: | (-)-Huperzine A-d7 major (>90%) is the labelled form of (-)-Huperzine A (H826000), a reversible alkaloid inhibitor of AChE which crosses the blood-brain barrier. A potential therapeutic agent for AlzheimerтАЩs disease. It reduces cell death induced by glutamate in primary cultures derived from forebrain, hippocampus, cortex and cerebellum of embryonic rat brain. |
Molecular Weight: | 249.36 |
Molecular Formula: | C15H11D7N2O |
Solubility: | Chloroform (Slightly), Methanol (Slightly) |
Appearance: | Light Brown to Brown Solid |
Storage: | 4°C, Inert atmosphere |
References: | Wang, Y.-E., et al. Acta Pharmacol. Sin., 7, 110 (1986), Ved, H.S., et al. Neuroreport, 8, 963 (1997). |
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