Description: | (-)-Huperzine A-d6 (Major) is the labelled form of (-)-Huperzine A (H826000), a reversible alkaloid inhibitor of AChE which crosses the blood-brain barrier. A potential therapeutic agent for Alzheimer's disease. It reduces cell death induced by glutamate in primary cultures derived from forebrain, hippocampus, cortex and cerebellum of embryonic rat brain. |
Molecular Weight: | 248.35 |
Molecular Formula: | C15H12D6N2O |
Melting Point: | 162 - 167°C |
Solubility: | Chloroform (Slightly), DMSO, Methanol (Slightly) |
Appearance: | Pale Brown to Light Brown Solid |
Storage: | Refrigerator, Under Inert Atmosphere |
References: | Wang, Y.-E., et al. Acta Pharmacol. Sin., 7, 110 (1986), Ved, H.S., et al. Neuroreport, 8, 963 (1997). |
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