Formic hydrazide - CAS 624-84-0
Catalog: |
BB031616 |
Product Name: |
Formic hydrazide |
CAS: |
624-84-0 |
Synonyms: |
formohydrazide |
IUPAC Name: | formohydrazide |
Description: | Formic hydrazide (CAS# 624-84-0) is used in the synthesis of azaindazoles as inhibitors of bacterial DNA ligase. Also used in the synthesis of anticonvulsants as quinoline derivatives. |
Molecular Weight: | 60.06 |
Molecular Formula: | CH4N2O |
Canonical SMILES: | C(=O)NN |
InChI: | InChI=1S/CH4N2O/c2-3-1-4/h1H,2H2,(H,3,4) |
InChI Key: | XZBIXDPGRMLSTC-UHFFFAOYSA-N |
Boiling Point: | 51-58 °C |
Density: | 1.325 g/cm3 |
MDL: | MFCD00007589 |
LogP: | 0.33320 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
US-2016031825-A1 | Substituted dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity | 20140731 |
US-2016031830-A1 | Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity | 20140731 |
US-9290457-B2 | Substituted dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity | 20140731 |
US-2015353571-A1 | 1,3-benzothiazinone sulfoxide and sulfone compounds | 20140609 |
US-2015353572-A1 | 1,3-benzothiazinone, sulfoxide, and sulfone compounds with electrophilic substituent | 20140609 |
PMID | Publication Date | Title | Journal |
23038643 | 20121105 | Robust helix formation in a new family of oligoureas based on a constrained bicyclic building block | Angewandte Chemie (International ed. in English) |
22901277 | 20120910 | VEGF-functionalized dextran has longer intracellular bioactivity than VEGF in endothelial cells | Biomacromolecules |
22800535 | 20120809 | Carbonylhydrazide-based molecular tongs inhibit wild-type and mutated HIV-1 protease dimerization | Journal of medicinal chemistry |
22830692 | 20120721 | Optimizing conical intersections of solvated molecules: the combined spin-flip density functional theory/effective fragment potential method | The Journal of chemical physics |
22798917 | 20120701 | 2-(4-Bromo-phen-yl)acetohydrazide | Acta crystallographica. Section E, Structure reports online |
Complexity: | 20 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 60.032362755 |
Formal Charge: | 0 |
Heavy Atom Count: | 4 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 60.032362755 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 55.1 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -2 |
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