Fmoc-N-amido-PEG2-propionic acid - CAS 872679-70-4
Catalog: |
BB038364 |
Product Name: |
Fmoc-N-amido-PEG2-propionic acid |
CAS: |
872679-70-4 |
Synonyms: |
Fmoc-N-amido-PEG2-acid; Fmoc-9-Amino-4,7-Dioxanonanoic acid; 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10-trioxa-4-azatridecan-13-oic acid; Fmoc-AEEP-OH; 13-(9H-Fluoren-9-yl)-11-oxo-4,7,12-trioxa-10-azatridecanoic Acid;?Fmoc-NH-PEG2-CH2CH2COOH; 9-(Fmoc-amino)-4,7-dioxanonanoic Acid; 2,7,10-Trioxa-4-azatridecan-13-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-; Fmoc-NH-PEG2-COOH; Fmoc-NH-PEG2-acid; Fmoc-PEG2-propionic acid; 3-[2-[2-(Fmoc-amino)ethoxy]ethoxy]propionic Acid; 9-(9H-Fluorene-9-ylmethoxycarbonylamino)-4,7-dioxanonanoic acid |
Related CAS: | 850312-72-0 (polymer)
|
IUPAC Name: | 3-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]propanoic acid |
Description: | Fmoc-NH-PEG2-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
Molecular Weight: | 399.44 |
Molecular Formula: | C22H25NO6 |
Canonical SMILES: | C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCC(=O)O |
InChI: | InChI=1S/C22H25NO6/c24-21(25)9-11-27-13-14-28-12-10-23-22(26)29-15-20-18-7-3-1-5-16(18)17-6-2-4-8-19(17)20/h1-8,20H,9-15H2,(H,23,26)(H,24,25) |
InChI Key: | QWHLFJJLRVOHTM-UHFFFAOYSA-N |
Boiling Point: | 622.1±55.0°C at 760 mmHg |
Melting Point: | 95.0-99.0°C |
Flash Point: | 330.0±31.5 °C |
Purity: | ≥95% |
Density: | 1.243±0.06 g/cm3 at 20°C, 760 Torr |
Solubility: | Soluble in DMSO, Methanol |
Appearance: | Colorless Oily Matter |
Storage: | Store at 2-8°C |
LogP: | 2.96 |
Vapor Pressure: | 0.0±1.9 mmHg at 25°C |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-112043839-A | Radioisotope-labeled polypeptide imaging agent targeting transferrin receptor and application thereof | 20200821 |
KR-20210108830-A | A nanostructure, a biosensor including the nanostructure, and a screening method | 20200226 |
US-2021262014-A1 | Nanostructure, a biosensor including the nanostructure, and a screening method | 20200226 |
WO-2020247297-A1 | Glucose-responsive insulin conjugates | 20190606 |
WO-2020236817-A2 | Mcl-1 inhibitor antibody-drug conjugates and methods of use | 20190520 |
Complexity: | 505 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 399.16818752 |
Formal Charge: | 0 |
Heavy Atom Count: | 29 |
Hydrogen Bond Acceptor Count: | 6 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 399.16818752 |
Rotatable Bond Count: | 12 |
Topological Polar Surface Area: | 94.1 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 2.3 |
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