Ethyl gallate - CAS 831-61-8

Catalog: BB036979
Product Name: Ethyl gallate
CAS: 831-61-8
Synonyms: ethyl 3,4,5-trihydroxybenzoate
Application: anti-oxidant
Ethyl gallate
IUPAC Name:ethyl 3,4,5-trihydroxybenzoate
Description:Ethyl gallate obviously decreases cell proliferation in MDA-MB-231 and MCF-7 cells in a dose- and time-dependent manner, exhibits cytotoxicity in a dose-dependent manner. Ethyl gallate can inhibit the abilities of invasion of breast cancer in vitro by inhibiting the mRNA levels of MMP-9/MMP-2, phosphorylation of Akt and protein expression of NF-κB. Ethyl gallate inhibits hydrogen peroxide signaling, may represent an alternative class of vasopressors for use in septic shock. Ethyl gallate suppresses proliferation and invasion in human breast cancer cells by modulating the PI3K/Akt pathway, which may contribute to inhibiting their downstream targets such as NF-κB p-65, Bcl-2/Bax, and mRNA levels of MMP-2 and MMP-9 in breast cancer cells, could be used as potential antioxidants with safe therapeutic application in cancer chemotherapy.
Molecular Weight:198.17
Molecular Formula:C9H10O5
Canonical SMILES:CCOC(=O)C1=CC(=C(C(=C1)O)O)O
InChI:InChI=1S/C9H10O5/c1-2-14-9(13)5-3-6(10)8(12)7(11)4-5/h3-4,10-12H,2H2,1H3
InChI Key:VFPFQHQNJCMNBZ-UHFFFAOYSA-N
Boiling Point:447.3 ℃ at 760 mmHg
Melting Point:160 - 162 °C
Purity:> 98 %
Density:1.424 g/cm3
Appearance:Powder
MDL:MFCD00016430
LogP:0.98010
Quality Standard:Enterprise Standard

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