Ethyl 4-hydroxy-2-methyl-1,1-dioxo-2H-1,2-benzothiazine-3-carboxylate - CAS 24683-26-9
Catalog: |
BB018578 |
Product Name: |
Ethyl 4-hydroxy-2-methyl-1,1-dioxo-2H-1,2-benzothiazine-3-carboxylate |
CAS: |
24683-26-9 |
Synonyms: |
ethyl 4-hydroxy-2-methyl-1,1-dioxo-1lambda6,2-benzothiazine-3-carboxylate |
IUPAC Name: | ethyl 4-hydroxy-2-methyl-1,1-dioxo-1λ6,2-benzothiazine-3-carboxylate |
Description: | Ethyl 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide is an impurity found in meloxicam. |
Molecular Weight: | 283.30 |
Molecular Formula: | C12H13NO5S |
Canonical SMILES: | CCOC(=O)C1=C(C2=CC=CC=C2S(=O)(=O)N1C)O |
InChI: | InChI=1S/C12H13NO5S/c1-3-18-12(15)10-11(14)8-6-4-5-7-9(8)19(16,17)13(10)2/h4-7,14H,3H2,1-2H3 |
InChI Key: | QWTNANUGXZEPFQ-UHFFFAOYSA-N |
Boiling Point: | 424.1 °C at 760 mmHg |
Melting Point: | 140-143 °C |
Purity: | 99 % |
Density: | 1.444 g/cm3 |
Appearance: | White solid |
MDL: | MFCD00190168 |
LogP: | 2.12910 |
GHS Hazard Statement: | H331 (89.13%): Toxic if inhaled [Danger Acute toxicity, inhalation] |
Precautionary Statement: | P261, P271, P304+P340, P311, P321, P403+P233, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
US-2021093642-A1 | STABLE AQUEOUS PARENTERAL SOLUTIONS OF NONSTEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs) | 20190926 |
WO-2021059234-A1 | Stable aqueous parenteral solutions of nonsteroidal anti-inflammatory drugs (nsaids) | 20190926 |
CN-101891737-A | Method for ammonolyzing and synthesizing meloxicam under catalysis of Lewis acid | 20090522 |
JP-2010173960-A | 2H-1,2-thiazine 1,1-dioxide derivatives | 20090129 |
AU-2007324354-A1 | Process for the purification of meloxicam | 20061120 |
PMID | Publication Date | Title | Journal |
20045318 | 20100201 | Discovery of cyclicsulfonamide derivatives as 11 beta-hydroxysteroid dehydrogenase 1 inhibitors | Bioorganic & medicinal chemistry letters |
Complexity: | 505 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 283.05144369 |
Formal Charge: | 0 |
Heavy Atom Count: | 19 |
Hydrogen Bond Acceptor Count: | 6 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 283.05144369 |
Rotatable Bond Count: | 3 |
Topological Polar Surface Area: | 92.3 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 3.2 |
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