Ethyl 2-aminothiazole-4-acetate - CAS 53266-94-7
Catalog: |
BB028112 |
Product Name: |
Ethyl 2-aminothiazole-4-acetate |
CAS: |
53266-94-7 |
Synonyms: |
ethyl 2-(2-amino-1,3-thiazol-4-yl)acetate |
IUPAC Name: | ethyl 2-(2-amino-1,3-thiazol-4-yl)acetate |
Description: | Ethyl 2-aminothiazole-4-acetate (CAS# 53266-94-7) is a versatile building block for the synthesis of various pharmaceutical and biologically active compounds including inhibitors and antibiotics. It is used in the synthesis of Cefdinir (C242675) derivatives. |
Molecular Weight: | 186.23 |
Molecular Formula: | C7H10N2O2S |
Canonical SMILES: | CCOC(=O)CC1=CSC(=N1)N |
InChI: | InChI=1S/C7H10N2O2S/c1-2-11-6(10)3-5-4-12-7(8)9-5/h4H,2-3H2,1H3,(H2,8,9) |
InChI Key: | SHQNGLYXRFCPGZ-UHFFFAOYSA-N |
Boiling Point: | 318.5 °C at 760 mmHg |
Purity: | 98 % |
Density: | 1.295 g/cm3 |
Appearance: | Slightly yellow to beige crystalline powder |
MDL: | MFCD00005330 |
LogP: | 1.41210 |
Publication Number | Title | Priority Date |
CN-113461635-A | 4- (2-chloroethyl) thiazole-2-carboxylic acid ethyl ester and preparation method and application thereof | 20210707 |
CN-111533710-A | Method for preparing cefotiam intermediate 2-aminothiazole-4-acetic acid by one-pot method | 20200602 |
CN-111662246-A | Mirabegron impurity compound and preparation method and application thereof | 20200515 |
CN-111153898-A | Thiourea derivative and preparation method and application thereof | 20190702 |
WO-2020257429-A1 | Ectonucleotidase inhibitors and methods of use thereof | 20190620 |
PMID | Publication Date | Title | Journal |
22719339 | 20120601 | Dichloridobis[ethyl 2-(2-amino-1,3-thia-zol-4-yl)acetate-κ(2)O,N(3)]cadmium | Acta crystallographica. Section E, Structure reports online |
21588949 | 20101009 | Ethyl 2-{(2Z)-2-[(1-naphthyl-sulfon-yl)imino]-2,3-dihydro-1,3-thia-zol-4-yl}acetate monohydrate | Acta crystallographica. Section E, Structure reports online |
21578564 | 20091104 | Bis(2-amino-thia-zole-4-acetato)aquazinc(II) | Acta crystallographica. Section E, Structure reports online |
21580862 | 20081018 | Bis(ethyl 2-amino-4-thia-zoleacetato-κN)silver(I) nitrate | Acta crystallographica. Section E, Structure reports online |
Complexity: | 166 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 186.04629874 |
Formal Charge: | 0 |
Heavy Atom Count: | 12 |
Hydrogen Bond Acceptor Count: | 5 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 186.04629874 |
Rotatable Bond Count: | 4 |
Topological Polar Surface Area: | 93.4 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.8 |
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Carbonyl Compounds
Oxazole/Thiazole
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS