Ethyl 2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetate - CAS 65052-66-6
Catalog: |
BB032623 |
Product Name: |
Ethyl 2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetate |
CAS: |
65052-66-6 |
Synonyms: |
(2Z)-2-(2-amino-4-thiazolyl)-2-methoxyiminoacetic acid ethyl ester; ethyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate |
IUPAC Name: | ethyl 2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate |
Description: | Ethyl 2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetate (CAS# 65052-66-6) is an intermediate for the synthesis of Anticefepime (A697490), which is an impurity of Cefepime (C242750), an fourth generation cephalosporin antibiotic. |
Molecular Weight: | 229.26 |
Molecular Formula: | C8H11N3O3S |
Canonical SMILES: | CCOC(=O)C(=NOC)C1=CSC(=N1)N |
InChI: | InChI=1S/C8H11N3O3S/c1-3-14-7(12)6(11-13-2)5-4-15-8(9)10-5/h4H,3H2,1-2H3,(H2,9,10)/b11-6- |
InChI Key: | POBMBNPEUPDXRS-WDZFZDKYSA-N |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-106632137-A | Method for preparing ethyl 2-(2-aminothiazole-4-yl)-2-methoxyiminoacetate | 20161229 |
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PMID | Publication Date | Title | Journal |
19545053 | 20090401 | [Synthesis and antibacterial activity of 7 beta-[2-(2-substituted aminothiazol-4-yl)-(Z)-2-methoxyiminoacetylamido]-3-quaternaryammoniummethyl-cephalosporins] | Yao xue xue bao = Acta pharmaceutica Sinica |
Complexity: | 260 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 229.05211239 |
Formal Charge: | 0 |
Heavy Atom Count: | 15 |
Hydrogen Bond Acceptor Count: | 7 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 229.05211239 |
Rotatable Bond Count: | 5 |
Topological Polar Surface Area: | 115 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 1 |
XLogP3: | 1.6 |
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