Ethyl 1H-Indazole-7-carboxylate - CAS 885278-74-0
Catalog: |
BB038947 |
Product Name: |
Ethyl 1H-Indazole-7-carboxylate |
CAS: |
885278-74-0 |
Synonyms: |
1H-indazole-7-carboxylic acid ethyl ester; ethyl 1H-indazole-7-carboxylate |
IUPAC Name: | ethyl 1H-indazole-7-carboxylate |
Description: | Ethyl 1H-Indazole-7-carboxylate (CAS# 885278-74-0) is useful for the synthesis of pyrrolopyrazines derivatives due to them acting as possible selective spleen tyrosine kinase inhibitors. |
Molecular Weight: | 190.20 |
Molecular Formula: | C10H10N2O2 |
Canonical SMILES: | CCOC(=O)C1=CC=CC2=C1NN=C2 |
InChI: | InChI=1S/C10H10N2O2/c1-2-14-10(13)8-5-3-4-7-6-11-12-9(7)8/h3-6H,2H2,1H3,(H,11,12) |
InChI Key: | AZOFSDWPAJNIAZ-UHFFFAOYSA-N |
Boiling Point: | 353.916 °C at 760 mmHg |
Density: | 1.272 g/cm3 |
MDL: | MFCD07371560 |
LogP: | 1.73960 |
Publication Number | Title | Priority Date |
EP-2763990-A1 | Pyrrolopyrazine kinase inhibitors | 20110901 |
EP-2763990-B1 | Pyrrolopyrazine kinase inhibitors | 20110901 |
JP-2014530172-A | Pyrrolopyrazine kinase inhibitor | 20110901 |
JP-6096778-B2 | Pyrrolopyrazine kinase inhibitor | 20110901 |
KR-20140074912-A | Pyrrolopyrazine kinase inhibitors | 20110901 |
Complexity: | 220 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 190.074227566 |
Formal Charge: | 0 |
Heavy Atom Count: | 14 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 190.074227566 |
Rotatable Bond Count: | 3 |
Topological Polar Surface Area: | 55 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.8 |
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Indazoles
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