Eprodisate disodium - CAS 36589-58-9
Catalog: |
BB023009 |
Product Name: |
Eprodisate disodium |
CAS: |
36589-58-9 |
Synonyms: |
disodium;propane-1,3-disulfonate |
Application: |
Used in the treatment of amyloid A (AA) amyloidosis. |
Related CAS: | 21668-77-9 (base)
|
IUPAC Name: | disodium;propane-1,3-disulfonate |
Description: | Eprodisate disodium is a sulfonated inhibitor of fibrillogenesis which coul be used in the treatment of amyloid A (AA) amyloidosis. |
Molecular Weight: | 248.19 |
Molecular Formula: | C3H6Na2O6S2 |
Canonical SMILES: | C(CS(=O)(=O)[O-])CS(=O)(=O)[O-].[Na+].[Na+] |
InChI: | InChI=1S/C3H8O6S2.2Na/c4-10(5,6)2-1-3-11(7,8)9;;/h1-3H2,(H,4,5,6)(H,7,8,9);;/q;2*+1/p-2 |
InChI Key: | DKGJFKPIUSHDIT-UHFFFAOYSA-L |
Purity: | > 98 % |
Density: | 1.773 g/cm3 |
Solubility: | Soluble in DMSO |
Appearance: | Solid powder |
Storage: | Store at 2-8 °C |
MDL: | MFCD00191483 |
LogP: | 0.62850 |
Quality Standard: | Enterprise Standard |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
WO-2021015219-A1 | Method for producing methylene disulfonate compound | 20190723 |
WO-2021015220-A1 | Method for producing cyclic disulfonic acid ester compound | 20190723 |
WO-2020263960-A1 | Compositions comprising a retinoid x receptor (rxr) agonist, a retinoic acid receptor (rar) agonist, or a dual rxr/rar agonist | 20190628 |
JP-6863347-B2 | Aqueous solution secondary battery | 20180731 |
TW-202003491-A | Piperazine azaspiro derivatives | 20180323 |
PMID | Publication Date | Title | Journal |
22528417 | 20120301 | Counterion condensation in short cationic peptides: limiting mobilities beyond the Onsager-Fuoss theory | Electrophoresis |
18671471 | 20080801 | Eprodisate in amyloid A amyloidosis: a novel therapeutic approach? | Expert opinion on pharmacotherapy |
18597009 | 20080401 | Gateways to clinical trials | Methods and findings in experimental and clinical pharmacology |
17577686 | 20070601 | Diagnostic performance of amyloid A protein quantification in fat tissue of patients with clinical AA amyloidosis | Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis |
17520107 | 20070401 | Gateways to clinical trials | Methods and findings in experimental and clinical pharmacology |
Complexity: | 227 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 3 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 247.94011882 |
Formal Charge: | 0 |
Heavy Atom Count: | 13 |
Hydrogen Bond Acceptor Count: | 6 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 247.94011882 |
Rotatable Bond Count: | 2 |
Topological Polar Surface Area: | 131 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
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