Enalapril - CAS 75847-73-3

Catalog: BB035417
Product Name: Enalapril
CAS: 75847-73-3
Synonyms: (2S)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid
Application: Enalapril is used in the treatment of hypertension, congestive heart failure, myocardial infarction, and diabetic nephropathies. lt decreases levels of angiotensin II leading to less vasoconstriction and decreased blood pressure by inhibiting ACE. lt lowers the death rate in systolic heart failure.
Enalapril
Related CAS:76095-16-4 (Maleate)
IUPAC Name:(2S)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid
Description:Enalapril is an angiotensin converting enzyme (ACE) inhibitor used in the treatment of hypertension, congestive heart failure, myocardial infarction, and diabetic nephropathies. Its IC50 values range from 2 to 800 nM. lt belongs to a class of medications called angiotensin converting enzyme inhibitors. pressure. lt decreases levels of angiotensin II leading to less vasoconstriction and decreased blood pressure by inhibiting ACE. lt has been shown to lower the death rate in systolic heart failure. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.
Molecular Weight:376.45
Molecular Formula:C20H28N2O5
Canonical SMILES:CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CCCC2C(=O)O
InChI:InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1
InChI Key:GBXSMTUPTTWBMN-XIRDDKMYSA-N
Boiling Point:582.4±50.0 °C | Condition: Press: 760 Torr
Melting Point:143-144 °C
Purity:98 %
Density:1.204±0.06 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
Solubility:DMSO 99 mg/mL; Water <1 mg/Ml
Appearance:White needle like crystal or crystalline powder
Storage:-20 °C Freezer
LogP:1.93340
Quality Standard:In-house standard
Stability:Stable under recommended storage conditions. /enalapril maleate/
Vapor Pressure:1.06X10-12 mm Hg at 25 °C (est)

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Related Functional Groups

Pyrrolidines

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