(E)-N-[2-(5-Hydroxy-3-indolyl)ethyl]-3-(4-hydroxy-3-methoxyphenyl)acrylamide - CAS 193224-22-5

Name: (E)-N-[2-(5-Hydroxy-3-indolyl)ethyl]-3-(4-hydroxy-3-methoxyphenyl)acrylamide
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB014936
Product Name:	(E)-N-[2-(5-Hydroxy-3-indolyl)ethyl]-3-(4-hydroxy-3-methoxyphenyl)acrylamide
CAS:	193224-22-5
Synonyms:	(E)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-3-(4-hydroxy-3-methoxyphenyl)-2-propenamide; (E)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-3-(4-hydroxy-3-methoxyphenyl)prop-2-enamide

Technical Data

IUPAC Name:	(E)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-3-(4-hydroxy-3-methoxyphenyl)prop-2-enamide
Description:	(E)-N-[2-(5-Hydroxy-3-indolyl)ethyl]-3-(4-hydroxy-3-methoxyphenyl)acrylamide (CAS# 193224-22-5 ) is a useful research chemical.
Molecular Weight:	352.38
Molecular Formula:	C20H20N2O4
Canonical SMILES:	COC1=C(C=CC(=C1)C=CC(=O)NCCC2=CNC3=C2C=C(C=C3)O)O
InChI:	InChI=1S/C20H20N2O4/c1-26-19-10-13(2-6-18(19)24)3-7-20(25)21-9-8-14-12-22-17-5-4-15(23)11-16(14)17/h2-7,10-12,22-24H,8-9H2,1H3,(H,21,25)/b7-3+
InChI Key:	WGHKJYWENWLOMY-XVNBXDOJSA-N
Melting Point:	115 - 117 °C
Appearance:	Solid
LogP:	3.35070

GHS Hazard Statement:	H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
Precautionary Statement:	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word:	Warning

Publication Number	Title	Priority Date
CN-111568829-A	High-content ceramide repair cream and preparation method thereof	20200603
KR-102171518-B1	Composition for Preventing or Treating Muscle Atrophy Comprising Lycii Radicis Cortex	20190221
KR-20200102348-A	Composition for Preventing or Treating Muscle Atrophy Comprising Lycii Radicis Cortex	20190221
US-2020306333-A1	Composition for preventing or treating muscle atrophy comprising lycii radicis cortex	20190221
US-11096981-B2	Composition for preventing or treating muscle atrophy comprising lycii radicis cortex	20190221

PMID	Publication Date	Title	Journal
22021176	20120501	Potent α-glucosidase inhibitors from safflower (Carthamus tinctorius L.) seed	Phytotherapy research : PTR
22386242	20120401	N-Caffeoyl serotonin as selective COX-2 inhibitor	Bioorganic & medicinal chemistry letters
21978225	20120101	Synthesis, biological activities and bioavailability of moschamine, a safflomide-type phenylpropenoic acid amide found in Centaurea cyanus	Natural product research
21648068	20111001	Effect of N-(p-coumaroyl)serotonin and N-feruloylserotonin, major anti-atherogenic polyphenols in safflower seed, on vasodilation, proliferation and migration of vascular smooth muscle cells	Molecular nutrition & food research
22125678	20111001	Study on the hypochlolesterolemic and antioxidative effects of tyramine derivatives from the root bark of Lycium chenese Miller	Nutrition research and practice

Complexity:	498
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	1
Exact Mass:	352.14230712
Formal Charge:	0
Heavy Atom Count:	26
Hydrogen Bond Acceptor Count:	4
Hydrogen Bond Donor Count:	4
Isotope Atom Count:	0
Monoisotopic Mass:	352.14230712
Rotatable Bond Count:	6
Topological Polar Surface Area:	94.6 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	3