(E)-N-[2-(3-Indolyl)ethyl]-3-(3,4-dihydroxyphenyl)acrylamide - CAS 945453-47-4
Catalog: |
BB041416 |
Product Name: |
(E)-N-[2-(3-Indolyl)ethyl]-3-(3,4-dihydroxyphenyl)acrylamide |
CAS: |
945453-47-4 |
Synonyms: |
(E)-3-(3,4-dihydroxyphenyl)-N-[2-(1H-indol-3-yl)ethyl]-2-propenamide; (E)-3-(3,4-dihydroxyphenyl)-N-[2-(1H-indol-3-yl)ethyl]prop-2-enamide |
IUPAC Name: | (E)-3-(3,4-dihydroxyphenyl)-N-[2-(1H-indol-3-yl)ethyl]prop-2-enamide |
Description: | (E)-N-[2-(3-Indolyl)ethyl]-3-(3,4-dihydroxyphenyl)acrylamide (CAS# 945453-47-4 ) is a useful research chemical. |
Molecular Weight: | 322.36 |
Molecular Formula: | C19H18N2O3 |
Canonical SMILES: | C1=CC=C2C(=C1)C(=CN2)CCNC(=O)C=CC3=CC(=C(C=C3)O)O |
InChI: | InChI=1S/C19H18N2O3/c22-17-7-5-13(11-18(17)23)6-8-19(24)20-10-9-14-12-21-16-4-2-1-3-15(14)16/h1-8,11-12,21-23H,9-10H2,(H,20,24)/b8-6+ |
InChI Key: | LNKPAQNDSCOUPS-SOFGYWHQSA-N |
LogP: | 3.34210 |
Publication Number | Title | Priority Date |
JP-2009263282-A | Melanin production inhibitor | 20080425 |
JP-5392742-B2 | Melanin production inhibitor | 20080425 |
PMID | Publication Date | Title | Journal |
22428927 | 20120425 | Safflomide increases the expression of adiponectin in vitro and in vivo: potential implication for hypoadiponectemia, visceral obesity, and insulin resistance | Journal of agricultural and food chemistry |
20673727 | 20100901 | Synthesis, biological evaluation, and structure-activity relationship study of novel cytotoxic aza-caffeic acid derivatives | Bioorganic & medicinal chemistry |
19524439 | 20090801 | N-[(Dihydroxyphenyl)acyl]serotonins as potent inhibitors of tyrosinase from mouse and human melanoma cells | Bioorganic & medicinal chemistry letters |
18524559 | 20081201 | Serotomide and safflomide modulate forskolin-stimulated cAMP formation via 5-HT1 receptor | Phytomedicine : international journal of phytotherapy and phytopharmacology |
17331819 | 20070601 | Synthesis of safflomide and its HPLC measurement in mouse plasma after oral administration | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences |
Complexity: | 454 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 1 |
Exact Mass: | 322.13174244 |
Formal Charge: | 0 |
Heavy Atom Count: | 24 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 4 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 322.13174244 |
Rotatable Bond Count: | 5 |
Topological Polar Surface Area: | 85.4 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 3 |
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