(E)-3-(3,4-Dihydroxyphenyl)-N-[2-(5-hydroxy-3-indolyl)ethyl]acrylamide - CAS 928765-97-3

Name: (E)-3-(3,4-Dihydroxyphenyl)-N-[2-(5-hydroxy-3-indolyl)ethyl]acrylamide
Brand: BOC Sciences
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Catalog:	BB040689
Product Name:	(E)-3-(3,4-Dihydroxyphenyl)-N-[2-(5-hydroxy-3-indolyl)ethyl]acrylamide
CAS:	928765-97-3
Synonyms:	(E)-3-(3,4-dihydroxyphenyl)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-propenamide; (E)-3-(3,4-dihydroxyphenyl)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]prop-2-enamide

Technical Data

IUPAC Name:	(E)-3-(3,4-dihydroxyphenyl)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]prop-2-enamide
Description:	(E)-3-(3,4-Dihydroxyphenyl)-N-[2-(5-hydroxy-3-indolyl)ethyl]acrylamide (CAS# 928765-97-3 ) is a useful research chemical.
Molecular Weight:	338.36
Molecular Formula:	C19H18N2O4
Canonical SMILES:	C1=CC(=C(C=C1C=CC(=O)NCCC2=CNC3=C2C=C(C=C3)O)O)O
InChI:	InChI=1S/C19H18N2O4/c22-14-3-4-16-15(10-14)13(11-21-16)7-8-20-19(25)6-2-12-1-5-17(23)18(24)9-12/h1-6,9-11,21-24H,7-8H2,(H,20,25)/b6-2+
InChI Key:	YXKFALZVRFVXFA-QHHAFSJGSA-N
LogP:	3.49710

Publication Number	Title	Priority Date
KR-101532866-B1	use of Zingiber cassumunar Roxb extracts or compounds isolated therefrom for enhancing melanogenesis	20140128
JP-2015010076-A	Biofilm formation inhibitor	20130701
EP-2790659-B1	Cosmetic composition for stimulating the cellular anti-aging functions of the skin	20111216
US-2015031740-A1	Cosmetic composition for stimulating the cellular anti-aging functions of the skin	20111216
WO-2013087834-A2	Cosmetic composition for stimulating the cellular anti-aging functions of the skin	20111216

PMID	Publication Date	Title	Journal
22386242	20120401	N-Caffeoyl serotonin as selective COX-2 inhibitor	Bioorganic & medicinal chemistry letters
21377874	20110401	Synthesis and structure-activity relationships of phenylpropanoid amides of serotonin on tyrosinase inhibition	Bioorganic & medicinal chemistry letters
21612159	20110401	Serotonin derivatives as inhibitors of beta-secretase (BACE 1)	Die Pharmazie
20655990	20101201	Cytoprotective activities of hydroxycinnamic acid amides of serotonin against oxidative stress-induced damage in HepG2 and HaCaT cells	Fitoterapia
19524439	20090801	N-[(Dihydroxyphenyl)acyl]serotonins as potent inhibitors of tyrosinase from mouse and human melanoma cells	Bioorganic & medicinal chemistry letters

Complexity:	484
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	1
Exact Mass:	338.12665706
Formal Charge:	0
Heavy Atom Count:	25
Hydrogen Bond Acceptor Count:	4
Hydrogen Bond Donor Count:	5
Isotope Atom Count:	0
Monoisotopic Mass:	338.12665706
Rotatable Bond Count:	5
Topological Polar Surface Area:	106
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	1.8