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| Description: | (E)-2-(3,4-Dihydro-7-methoxy-1(2H)-naphthalenylidene)ethanamine is an intermediate used in the synthesis of (E)-N-[2-(3,4-Dihydro-7-methoxy-1(2H)-naphthalenylidene)ethyl]acetamide(Agomelatine Impurity) (D450485), which is an impurity of Agomelatine (A430000) which is a melatoninergic agonist and selective antagonist of 5-HT2C receptors and used in the treatment of major depressive disorder. Agomelatine Impurity 2 |
| Molecular Weight: | 203.28 |
| Molecular Formula: | C13H17NO |
| References: | Yous, S., et al. J. Med. Chem., 35, 1484 (1992), Zhdanova, I., et al. J. Clin. Endocrinol. Metab., 86, 4727 (2001), Cajochen, C., et al. J. Pineal Res., 35, 149 (2003),. |
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