DSP Crosslinker - CAS 57757-57-0
Catalog:
BB029805
Product Name:
DSP Crosslinker
CAS:
57757-57-0
Synonyms:
Disuccinimido dithiobispropionate; Di(N-succinimidyl) 3,3'-dithiodipropionate; Dithiobis(succinimidylpropionate); DTSP; Bis(2,5-dioxopyrrolidin-1-yl) 3,3'-disulfanediyldipropanoate
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BB029805
10 g
$680
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IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 3-[[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropyl]disulfanyl]propanoate
Description: DSP Crosslinker is a cleavable crosslinker. It is typically coupled to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5).
Molecular Weight: 404.42
Molecular Formula: C14H16N2O8S2
Canonical SMILES: C1CC(=O)N(C1=O)OC(=O)CCSSCCC(=O)ON2C(=O)CCC2=O
InChI: InChI=1S/C14H16N2O8S2/c17-9-1-2-10(18)15(9)23-13(21)5-7-25-26-8-6-14(22)24-16-11(19)3-4-12(16)20/h1-8H2
InChI Key: FXYPGCIGRDZWNR-UHFFFAOYSA-N
Boiling Point: 560.1±60.0 °C (Predicted)
Melting Point: 128-133 °C
Flash Point: 292.6±32.9 °C
Purity: 95%
Density: 1.570±0.10 g/cm3 (Predicted)
Solubility: 10 mm in DMSO
Appearance: Off-White Solid
Storage: Store at 2-8 °C
LogP: -1.66
Vapor Pressure: 0.0±1.5 mmHg at 25°C
GHS Hazard Statement: H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
Precautionary Statement: P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word: Warning
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PMID Publication Date Title Journal
24419339 20140101 DSTP-27 prevents entry of human cytomegalovirus Antimicrobial agents and chemotherapy
22763413 20120821 Simple, sensitive and selective detection of dopamine using dithiobis(succinimidylpropionate)-modified gold nanoparticles as colorimetric probes The Analyst
22644737 20120801 A negative ion mass spectrometry approach to identify cross-linked peptides utilizing characteristic disulfide fragmentations Journal of the American Society for Mass Spectrometry
22608456 20120530 Influence of macroporous gold support and its functionalization on lactate oxidase-based biosensors response Talanta
22297859 20120301 Probe functionalization with a Rhop-3 antibody: toward a Rhop-3 antigen immunosensor for detection of malaria Analytical and bioanalytical chemistry
Complexity: 552
Compound Is Canonicalized: Yes
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Exact Mass: 404.03480782
Formal Charge: 0
Heavy Atom Count: 26
Hydrogen Bond Acceptor Count: 10
Hydrogen Bond Donor Count: 0
Isotope Atom Count: 0
Monoisotopic Mass: 404.03480782
Rotatable Bond Count: 11
Topological Polar Surface Area: 178 Å2
Undefined Atom Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
XLogP3: -1.2
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