Docetaxel 2'-tert-Butyldimethylsilyl 7,10-Tris(triethylsilyl) Ether - CAS 195141-96-9

Catalog: BB068636
Product Name: Docetaxel 2'-tert-Butyldimethylsilyl 7,10-Tris(triethylsilyl) Ether
CAS: 195141-96-9
Synonyms: (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-4,6-bis[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl (αR,βS)-β-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-benzenepropanoic Acid Ester
Description:Docetaxel 2'-tert-Butyldimethylsilyl 7,10-Tris(triethylsilyl) Ether is an intermediate used in the synthesis of 2-Debenzoyl-2-pentenoyldocetaxel (D205050), which is a related compound of Docetaxel (D494420), a chemotherapy drug that exhibits anti-mitotic properties and used for treating various metastatic cancers.
Molecular Weight:1150.66
Molecular Formula:C61H95NO14Si3
Solubility:Chloroform; Methanol
Appearance:White Solid
Storage:Refrigerator, under inert atmosphere
References:Yokoyama, G., et al.: Int J Clin Oncol 10, 139 (2005); Ringel, I., et al. J. Natl. Cancer Inst., 83, 288 (1991), Extra, J.-M., et al. Cancer Res., 53, 1037 (1993).

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