Dimethyl (3-Chloro-4-fluorophenyl)aspartate

Catalog: BB055726
Product Name: Dimethyl (3-Chloro-4-fluorophenyl)aspartate
Synonyms: (3-Chloro-4-fluorophenyl)aspartate Dimethyl Ester
Description:Dimethyl (3-Chloro-4-fluorophenyl)aspartate is an intermediate in the synthesis of Afatinib Maleic Acid Adduct (A355318), an impurity of Afatinib (A355300); an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.
Molecular Weight:289.69
Molecular Formula:C12H13ClFNO4
Solubility:Dichloromethane
Appearance:Orange oil
References:Schroeder, J., et al. PCT Int. Appl. WO 2007085638 A1 20070802. Aug 2, 2007.

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