Diethylene Glycol Monopropargyl Ether - CAS 7218-43-1
Catalog: |
BB034565 |
Product Name: |
Diethylene Glycol Monopropargyl Ether |
CAS: |
7218-43-1 |
Synonyms: |
Propargyl-PEG3-alcohol; Propargyl-PEG2-alcohol; 2-[2-(2-Propynyloxy)ethoxy]ethanol; 3,6-Dioxa-8-nonyn-1-ol; Ethanol, 2-(2-(2-propynyloxy)ethoxy)-; Diethylene Glycol Mono(2-propyn-1-yl) Ether; 2-(2-(prop-2-yn-1-yloxy)ethoxy)ethan-1-ol |
Related CAS: | 32199-97-6 (polymer)
|
IUPAC Name: | 2-(2-prop-2-ynoxyethoxy)ethanol |
Description: | Diethylene Glycol Monopropargyl Ether is a polyethylene glycol (PEG)-based PROTAC linker that can be used in the synthesis of a series of PROTACs. |
Molecular Weight: | 144.17 |
Molecular Formula: | C7H12O3 |
Canonical SMILES: | C#CCOCCOCCO |
InChI: | InChI=1S/C7H12O3/c1-2-4-9-6-7-10-5-3-8/h1,8H,3-7H2 |
InChI Key: | HUSDTFBXUYBZJD-UHFFFAOYSA-N |
Boiling Point: | 81°C at 1 mmHg |
Purity: | >97% |
Density: | 1.06±0.06 g/cm3 (Predicted) |
Solubility: | Soluble in Acetone, Chloroform, Ethanol, Ethyl Acetate |
Appearance: | Colorless to Pale Yellow Oily Matter |
Storage: | Store at 2-8°C under inert gas (nitrogen or Argon) |
LogP: | -0.35490 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
WO-2021067606-A1 | Brm targeting compounds and associated methods of use | 20191001 |
WO-2020206424-A1 | Stat degraders and uses thereof | 20190405 |
TW-202106676-A | Stat degraders and uses thereof | 20190405 |
TW-202102523-A | Multivalent d-peptidic compounds for target proteins | 20190322 |
WO-2020014489-A2 | Dimeric immuno-modulatory compounds against cereblon-based mechanisms | 20180711 |
Complexity: | 103 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 144.078644241 |
Formal Charge: | 0 |
Heavy Atom Count: | 10 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 144.078644241 |
Rotatable Bond Count: | 6 |
Topological Polar Surface Area: | 38.7 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -0.6 |
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