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| Description: | Diethyl 2-[(3,4-Dichloroanilino)methylene]malonate is used in the preparation of 6,8-Dichloroquinolones which exhibits intense anti-bacterial activity against E. coli and S. aureus;Also, it is an intermediate used in the synthesis of 6-Chloro-6-defluoro Ciprofloxacin (C368035), which is an impurity of Ciprofloxacin (C482500), which is a fluorinated quinolone antibacterial. |
| Molecular Weight: | 332.18 |
| Molecular Formula: | C14H15Cl2NO4 |
| References: | Pintilie, L., et al. Rom. (2017), RO 129982 B1 20170130; Hoffken, G., et al. Antimicrob. Ag. Chemother., 27, 375 (1985), Scully, B.E., et al. Lancet, 1, 819 (1986). |
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