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| Description: | di-tert-butyl (4,5,6,7-Tetrahydrobenzo[d]thiazole-2,6-diyl)dicarbamate is a by-product in the synthesis of Pramipexole Dimer Impurity (P700730) which is derived from Pramipexole (P700750). Antiparkinsonian. Pramipexole (Mirapex, Mirapexin, Sifrol) is a non-ergoline dopamine agonist indicated for treating early-stage Parkinson's disease (PD) and restless legs syndrome (RLS).[1] It is also sometimes used off-label as a treatment for cluster headache and to counteract the problems with sexual dysfunction experienced by some users of the selective serotonin reuptake inhibitor (SSRI) antidepressants. |
| Molecular Weight: | 369.48 |
| Molecular Formula: | C17H27N3O4S |
| Solubility: | MeOH, DMSO, CH2Cl2 |
| Appearance: | Yellow Gel |
| References: | Mierau, J., et al. J. Med. Chem., 30, 494 (1987), Schilling, J.C., et al. Clin. Pharmacol. Ther., 51, 541 (1992), Kieburtz, K., et al. J. Am. Med. Assoc., 278, 125 (1997). |
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