Disuccinimidyl glutarate - CAS 79642-50-5
Catalog: |
BB036388 |
Product Name: |
Disuccinimidyl glutarate |
CAS: |
79642-50-5 |
Synonyms: |
DSG Crosslinker; Di(N-succinimidyl) glutarate; Bis(2,5-dioxopyrrolidin-1-yl) glutarate |
IUPAC Name: | bis(2,5-dioxopyrrolidin-1-yl) pentanedioate |
Description: | DSG is a membrane-permeable and non-cleavable crosslinker, allowing for intracellular labeling of peptides and proteins. |
Molecular Weight: | 326.26 |
Molecular Formula: | C13H14N2O8 |
Canonical SMILES: | C1CC(=O)N(C1=O)OC(=O)CCCC(=O)ON2C(=O)CCC2=O |
InChI: | InChI=1S/C13H14N2O8/c16-8-4-5-9(17)14(8)22-12(20)2-1-3-13(21)23-15-10(18)6-7-11(15)19/h1-7H2 |
InChI Key: | LNQHREYHFRFJAU-UHFFFAOYSA-N |
Boiling Point: | 485.1±55.0 °C at 760 mmHg |
Flash Point: | 247.2±31.5 °C |
Purity: | 99.3 % |
Density: | 1.5±0.1 g/cm3 |
Solubility: | Soluble in DMF, DMSO |
Appearance: | Off-white Powder |
Storage: | Store at -20 °C, keep in dry and avoid sunlight. |
LogP: | -3.30 |
Vapor Pressure: | 0.0±1.2 mmHg at 25°C |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-111943995-A | Oligosaccharide, glycoprotein conjugate, preparation method and application thereof | 20200821 |
WO-2021198965-A1 | Neodegrader conjugates | 20200331 |
WO-2021154933-A1 | Uv excitable polyfluorene based conjugates and their use in methods of analyte detection | 20200130 |
WO-2021119550-A1 | Method for determination of 3d genome architecture with base pair resolution and further uses thereof | 20191213 |
WO-2021113527-A1 | Antibodies that disrupt the interaction of gal3 and insulin receptor or integrins and methods of use thereof | 20191206 |
PMID | Publication Date | Title | Journal |
22247554 | 20120302 | Characterizing phospholamban to sarco(endo)plasmic reticulum Ca2+-ATPase 2a (SERCA2a) protein binding interactions in human cardiac sarcoplasmic reticulum vesicles using chemical cross-linking | The Journal of biological chemistry |
17924399 | 20080201 | Epitope mapping on bovine prion protein using chemical cross-linking and mass spectrometry | Journal of mass spectrometry : JMS |
17563120 | 20070703 | Conformational adaptation of apolipoprotein A-I to discretely sized phospholipid complexes | Biochemistry |
17458546 | 20070601 | Base sequence- and T m-dependent DNA oligomer separation by open tubular capillary columns carrying complementary DNA oligomers as probes | Analytical and bioanalytical chemistry |
16753217 | 20070201 | Mutagenesis, biochemical, and biophysical characterization of Mycoplasma arthritidis-derived mitogen | Molecular immunology |
Complexity: | 503 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 326.07501541 |
Formal Charge: | 0 |
Heavy Atom Count: | 23 |
Hydrogen Bond Acceptor Count: | 8 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 326.07501541 |
Rotatable Bond Count: | 8 |
Topological Polar Surface Area: | 127 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -1.5 |
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Carbonyl Compounds
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS