Dexamethasone 21-phosphate disodium salt - CAS 2392-39-4

Name: Dexamethasone 21-phosphate disodium salt
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB018247
Product Name:	Dexamethasone 21-phosphate disodium salt
CAS:	2392-39-4
Synonyms:	(11β,16α)-9-Fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)pregna-1,4-diene-3,20-dione disodium salt; Baldex; Colvasone; Corson; Dalalone; Decadron phosphate; Decdan; Desashock; Dexabene; Dexacort; Dexadreson; Dexagel; Dexagro; Dexamethasone 21-(disodium phosphate); Dexamethasone disodium phosphate; Dexamethasone phosphate disodium salt; Dexamethasone phosphate sodium salt; Dexamethasone sodium phosphate; Dexamethazone sodium phosphate; Dezone; Disodium dexamethasone 21-monophosphate; Disodium dexamethasone 21-phosphate; Disodium dexamethasone phosphate; Maxidex Ointment; Megacort; Onadron; Orgadrone; Sodium dexamethasone phosphate; Soldesam; Solu-Deca; Solu-Decadron; Spersadex; Turbinaire

Technical Data

Related CAS:	55203-24-2 (Deleted CAS) 2588541-26-6 (Deleted CAS) 312-93-6 (free acid)
IUPAC Name:	disodium;[2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate
Description:	Dexamethasone phosphate is a water-soluble form of the synthetic glucocorticoid dexamethasone. Dexamethasone binds the human glucocorticoid receptor with a higher affinity than a natural ligand, cortisol. Through receptor activation, dexamethasone has both transactivating and transrepressing effects on gene expression, producing, in general, anti-inflammatory results in clinical trials.
Molecular Weight:	516.40
Molecular Formula:	C22H28FNa2O8P
Canonical SMILES:	CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COP(=O)([O-])[O-])O)C)O)F)C.[Na+].[Na+]
InChI:	InChI=1S/C22H30FO8P.2Na/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30;;/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30);;/q;2*+1/p-2/t12-,15+,16+,17+,19+,20+,21+,22+;;/m1../s1
InChI Key:	PLCQGRYPOISRTQ-FCJDYXGNSA-L
Melting Point:	233-235 °C
Purity:	≥95%
Solubility:	Soluble in Water
Appearance:	White to off-white powder
Storage:	Store at 2-8 °C
MDL:	MFCD00079105
LogP:	2.88910

GHS Hazard Statement:	H302 (80.62%): Harmful if swallowed [Warning Acute toxicity, oral]
Precautionary Statement:	P201, P202, P260, P261, P264, P270, P271, P281, P301+P312, P304+P312, P304+P340, P308+P313, P312, P314, P330, P405, and P501
Signal Word:	Danger

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Complexity:	962
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	3
Defined Atom Stereocenter Count:	8
Defined Bond Stereocenter Count:	0
Exact Mass:	516.13012157
Formal Charge:	0
Heavy Atom Count:	34
Hydrogen Bond Acceptor Count:	9
Hydrogen Bond Donor Count:	2
Isotope Atom Count:	0
Monoisotopic Mass:	516.13012157
Rotatable Bond Count:	3
Topological Polar Surface Area:	147 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0