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| IUPAC Name: | (Z)-N-(1,3-dihydroxypropan-2-yl)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]-5-oxocyclopentyl]hept-5-enamide |
| Description: | Desisopropyl N-Dihydroxypropyl Dehydrolatanoprostamide is a useful reagent for developing methods for treating epithelial-related conditions including hair loss. Desisopropyl N-Dihydroxypropyl Dehydrolatanoprostamide is also an analog of Bimatoprost (B386800), an synthetic prostamide and structurally related to prostaglandin F2α. |
| Molecular Weight: | 459.58 |
| Molecular Formula: | C26H37NO6 |
| Canonical SMILES: | C1C(C(C(C1=O)CC=CCCCC(=O)NC(CO)CO)C=CC(CCC2=CC=CC=C2)O)O |
| InChI: | InChI=1S/C26H37NO6/c28-17-20(18-29)27-26(33)11-7-2-1-6-10-22-23(25(32)16-24(22)31)15-14-21(30)13-12-19-8-4-3-5-9-19/h1,3-6,8-9,14-15,20-23,25,28-30,32H,2,7,10-13,16-18H2,(H,27,33)/b6-1-,15-14+/t21-,22+,23+,25+/m0/s1 |
| InChI Key: | NYRITJWASKBGOC-KVXGTMRFSA-N |
| References: | Lipkin, P. and Lubit, B. US 7514474 B2 20090407 (2009); Lipkin, P. and Lubit, B U.S. Pat. Appl. Publ. US 20110002866 A1 20110106 (2011); Brandt, J.D., et al. Ophthalmology, 108, 1023 (2001); Woodward, D.F., et al. J. Pharmacol. Exp. Ther., 305, 772 (2003); Quinones, R., et al. J. Ocul. Pharmacol. Ther., 20, 115 (2004). |
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