Desfluoro-Abemaciclib

Catalog: BB068752
Product Name: Desfluoro-Abemaciclib
Synonyms: N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine
Description:Desfluoro-Abemaciclib is an impurity of Abemaciclib (A115153) is a potent and selective inhibitor of cyclin-dependent kinases, CDK4 and CDK6, as a method to inhibit the proliferation of cancer cells.
Molecular Weight:488.62
Molecular Formula:C27H33FN8
References:O'Leary, Ben., et al. Nat Rev Clin Oncol., 13, 417 (2016); Van Arsdale., et al. Clin. Cancer Res., 21, 2905 (2015).

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