Inquiry Basket
| Description: | Des-(Pyrazino[2,1-b][1,3]oxazin-2-yl) 4-(3-hydroxy)piperazin-1-yl Venetoclax-M27 is an intermediate in the synthesis of Venetoclax-M27 (V121010), a derivative of Venetoclax (ABT 199), which is a potent and selective BCL-2 inhibitor that achieves potent antitumour activity while sparing platelets. It's practical application is to treat chronic lymphocytic leukaemic cells and estrogen receptor-positive breast cancer. |
| Molecular Weight: | 884.45 |
| Molecular Formula: | C45H50ClN7O8S |
| References: | Davids, M. & Letai, A. Cancer Cell, 23, 139 (2013); Souers, A., et al. Nat. Med., 19, 202 (2013); Vaillant, F., et al. Cancer Cell, 24, 120 (2013); Vogler, M., et al. Brit. J. Haematol., 163, 139 (2013). |
Catalog: BB006975
(3R)-N-methyloxolan-3-amine hydrochloride
Detail
Catalog: BB077194
(S)-(-)-1,2-epoxydecane
Detail
![2-amino-3-{pyrrolo[2,1-f][1,2,4]triazin-5-yl}propanenitrile](https://resource.bocsci.com/structure/2092670-62-5.gif)
Catalog: BB016437
2-amino-3-{pyrrolo[2,1-f][1,2,4]triazin-5-yl}propanenitrile
Detail
Catalog: BB054808
2-(4-Aminooxan-3-yl)acetic Acid
Detail
Catalog: BB000560
6(5H)-Phenanthridinone
Detail
![4-chloro-6-methylimidazo[2,1-f][1,2,4]triazine](https://resource.bocsci.com/structure/2090251-00-4.gif)
Catalog: BB016398
4-chloro-6-methylimidazo[2,1-f][1,2,4]triazine
Detail
Catalog: BB054100
Azetidine
Detail
Catalog: BB012200
8-(tetramethyl-1,3,2-dioxaborolan-2-yl)-4H-chromen-4-one
Detail
Customer Support
If the product you need is not in our catalog, please contact us in time to submit your needs. You can help our website get better and better. Why not submit the request today?
Customer Centered
Global Delivery
Warehouses in multiple cities to ensure fast delivery
Quality Assurance
Strict process parameter control to ensure product quality
Large Stock
> 20,000 building blocks and intermediates from stock
Process Scale-up
Process scale-up from lab to industrial scale
Flexible Batch Size
Flexible batch size for diverse industrial demandsRelated Functional Groups
Other Building Blocks
Customers Also Viewed
N-[2-(4-oxo-4H-3,1-benzoxazin-2-yl)phenyl]-2-naphthalenesulfonamide
Pentane, 1,1,1,2,2,3,4,5,5,5-decafluoro-3-methoxy-4-(trifluoromethyl)-
Copyright © 2024 BOC Sciences. All rights reserved.
Our Products
