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| IUPAC Name: | 6-fluoropyrazine-2-carboxamide |
| Description: | Des-(3,4-dihydrogen-3-oxo) Favipiravir is a building block related to Favipiravir (CAT# F103350). Favipiravir is used for the treatment of advanced Ebola virus infection in a small animal model. Favipiravir suppressed the replication of Zaire Ebola virus and prevented a lethal outcome in 100% of the animals. Based on the studies, Favipiravir can be a candidate for the treatment of Ebola hemorrhagic fever. Des-(3,4-dihydrogen-3-oxo) Favipiravir may be useful in the preparation of novel pyrazine derivatives as antiviral agents. |
| Molecular Weight: | 141.1 |
| Molecular Formula: | C5H4FN3O |
| Canonical SMILES: | C1=C(N=C(C=N1)F)C(=O)N |
| InChI: | InChI=1S/C5H4FN3O/c6-4-2-8-1-3(9-4)5(7)10/h1-2H,(H2,7,10) |
| InChI Key: | HWULEHIEUIJINT-UHFFFAOYSA-N |
| References: | Oestereich, L., et al. Antiviral Res., 105, 17 (2014); Baranovich, T., et al. J. Virol. 87, 3741 (2013); Chem. and Eng. News p.8, Dec. 1 (2014); Egawa, H., et al. PCT Int. Appl., 137 pp. (2001). |
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